Figure 13 | Scientific Reports

Figure 13

From: Non-canonical WNT-signaling controls differentiation of lymphatics and extension lymphangiogenesis via RAC and JNK signaling

Figure 13

WNT5A-induced JNK phosphorylation is blocked by RAC and JNK inhibitors. Western blot of lysates from HD-LECs treated for 30 min with WNT5A. Lanes 1,2: Negative controls. Lane 3: Induction of p-JNK by WNT5A. Lane 4: Induction of p-JNK is inhibited by the JNK-inhibitor SP600125. Lane 5: Induction of p-JNK is inhibited by the RAC-inhibitor EHT1864. Expression of total JNK (tJNK) and α-tubulin are shown. (Complete original blot see: Suppl. Fig. 6).

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