Table 2 Outcomes of controlled ovarian stimulation, fertilization, and embryo transfer.
Variable | Low responders (n = 358) | Intermediate responders (n = 1,649) | High responders (n = 344) | p value |
|---|---|---|---|---|
Duration of stimulation (d) | 8.89 ± 1.92 | 9.05 ± 1.95 | 9.20 ± 1.77 | <0.01c |
Total dose of Gn (IU) | 1929.52 ± 746.47 | 1795.21 ± 678.77 | 1682.63 ± 669.46 | <0.01a,b,c |
Endometrial thickness on hCG day(mm) | 11.08 ± 2.1 | 11.33 ± 2.1 | 11.35 ± 2.0 | NS |
LH level on hCG day (IU/L) | 4.73 ± 3.98 | 4.10 ± 3.32 | 3.53 ± 2.83 | <0.05a,b,c |
E2 level on hCG day (pg/mL) | 2168.01 ± 1561.77 | 3873.55 ± 2118.79 | 6095.13 ± 2587.22 | <0.01a,b,c |
P level on hCG day (ng/mL) | 1.03 ± 1.48 | 1.17 ± 1.10 | 1.47 ± 1.26 | <0.01a,b,c |
No. of oocytes retrieved | 3.77 ± 1.20 | 11.40 ± 3.57 | 22.90 ± 4.23 | <0.01a,b,c |
No. of 2PN oocytes | 2.53 ± 1.17 | 6.94 ± 3.38 | 14.27 ± 4.87 | <0.01a,b,c |
2PN rate (%) | 907/1009 (89.89) | 11440/13160 (86.93) | 4909/5771 (85.06) | <0.01a,b,c |
No. of good-quality embryos | 1.31 ± 1.09 | 3.54 ± 2.58 | 7.12 ± 4.03 | <0.01a,b,c |
Good-quality embryos rate (%) | 468/795 (58.87) | 5836/9701 (60.16) | 2450/4137 (59.22) | NS |
No. of embryos transferred | 1.72 ± 0.54 | 2.05 ± 0.38 | 2.06 ± 0.28 | <0.01a,c |
At least one good-quality embryo transferred rate (%) | 266/358 (74.30) | 1512/1649 (91.69) | 331/344 (96.22) | <0.01a,b,c |
No. of embryos frozen | 1.65 ± 0.61 | 3.92 ± 2.35 | 7.56 ± 4.4 | <0.01a,b,c |
Clinical pregnancy rate (%) | 80/358 (22.35) | 533/1649 (32.32) | 96/344 (27.91) | <0.01a |
Implantation rate (%) | 94/617 (15.24) | 636/3378 (18.83) | 110/707 (15.56) | <0.05a,b |
Live birth rate (%) | 59/358 (16.48) | 398/1649 (24.15) | 69/344 (20.05) | <0.01a |