Figure 3
Influence of age and gender on cirDNA concentration in healthy individuals. Boxplot analysis of cirDNA concentration extracted from healthy individuals (N = 104), with regards to age (A,D) and gender (B,E). (C,F) Multivariate analysis representations. NcirDNA (A–C) and McirDNA (D–F) concentrations are expressed in copy number/ml of plasma. Boxplot represent median with min to max of values. Mann-Whitney U test was performed for univariate analysis and logistic regression was performed for multivariate analysis. Odds ratio (OR) with 95% confidence intervals (CIs) are represented. A probability of ≤0.05 was considered to be statistically significant; *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001.
