Figure 3

The mutational sites and interacting residues. The structures are colored as the following: HM-CCR2 (yellow), and the NMR-CXCR1 (red). The local structure near the mutation sites and the neighboring residues: (a) M61^1.54, L81^2.46 and L127^3.42; (b) L126^3.41 and P214^5.50; (c) K154^4.43; (d) R135^3.50 and A240^6.33; (e) W255^6.48 and G294^7.32.