Figure 8 | Scientific Reports

Figure 8

From: Functional and structural similarities of D7 proteins in the independently-evolved salivary secretions of sand flies and mosquitoes

Figure 8

C-terminal domain structures of long-form D7 and related proteins. Models of the C-terminal domains of P. duboscqi ABI15936 (A), hemolymph mJHBP from Ae. aegypti (B), AnStD7L1 salivary D7 from An. stephensi (C), and AeD7 salivary D7 from Ae. aegypti (D). The C-terminal domains are oriented in the same view by superposition, and key helical elements from each are labeled. The proteins show a continuum of increasing complexity and size from left to right, with the most complex, AeD7 containing a true internal binding pocket which contains a bound norepinephrine molecule having carbon atoms colored light grey, and nitrogen colored blue.

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