Figure 3 | Scientific Reports

Figure 3

From: Simulated microgravity promotes the formation of tridimensional cultures and stimulates pluripotency and a glycolytic metabolism in human hepatic and biliary tree stem/progenitor cells

Figure 3

Transcriptional analysis of mature hepatocyte markers in hBTSCs in simulated microgravity (SMG). The gene expression of ALB in hBTSCs cultured in SMG on Cytodex 3 microcarriers in presence of HDM compared to the expression of the same cells in NG (*p < 0.05; n = 4) (a). Levels of CYP3A4 significantly dropped down when hBTSCs were cultured in HDM in SMG (*p < 0.05; n = 4). They were restored when cells were put back in NG conditions, both cultured as a monolayer (2D) and on Cytodex 3 microcarriers (3D) (b).

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