Figure 3
From: Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-β oligomers
RD2 as potential inhibitor of enzymes contained in SGF, SIF, plasma and liver microsomes. Potential inhibition of the degradation of the l-peptide KLVFFRRRRRR (l-Pep) by RD2 was investigated in SGF (A), SIF (B), human plasma (C) and human liver microsomes (D) after immediate extraction and incubation for 5 min (SGF, SIF) or 30 min (plasma, liver microsomes). SGF, SIF, plasma and liver microsomes without peptides served as controls. RD2 did not influence the degradation of the l-peptide in any of the media.
