Table 11 Urinary parameters with significant differences compared to the control animals.

From: Toxicological testing of allogeneic secretome derived from peripheral mononuclear cells (APOSEC): a novel cell-free therapeutic agent in skin disease

Parameter

Increase ↑

Decrease ↓

Group/Sex

Test

day

Statistical

significance

Reason

Specific gravity

1.0112

0.0048

4 f

−6

p ≤ 0.05

B

pH value

6.63

0.86

2 m

28

p ≤ 0.05

A

6.72

0.53

4 m

28

p ≤ 0.01

A

7.62

0.19

4 f

28

p ≤ 0.05

A

  1. Differences are not considered to be test item-related.
  2. m: male.
  3. A: the slight alteration in comparison to control animals is without any biological relevance.
  4. B: effect observed before start of treatment.
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