Table 6 Changes in neuropharmacological parameters compared to group 1 (control) in treatment groups 2, 3 and 4 one hour after administration. Data are given in deviation to normal value.
Group 2 | Group 3 | Group 4 | ||
|---|---|---|---|---|
Awareness | Alertness | 0 | −1 | −1 |
Visual placing | 0 | −4 | −4 | |
Passivity | 0 | +2 | +2 | |
Stereotypy | 0 | 0 | 0 | |
Mood | Grooming | 0 | −4 | −4 |
Vocalisation | 0 | 0 | 0 | |
Restlessness | 0 | 0 | 0 | |
Aggression | 0 | 0 | 0 | |
Motor activity | Reactivity | 0 | 0 | −4 |
Spontaneous acitvity | 0 | −1 | −2 | |
Touch response | 0 | −4 | −4 | |
Pain response | 0 | −2 | −2 | |
CNS excitation | Startle response | 0 | 0 | −2 |
STRAUB tail | 0 | 0 | 0 | |
Tremor | 0 | 0 | 0 | |
Twitching | 0 | 0 | 0 | |
Convulsion | 0 | 0 | 0 | |
Posture | Body posture | 0 | −4 | −4 |
Limb position | 0 | −4 | −4 | |
Staggering gait | 0 | +2 | +2 | |
Abnormal gait | 0 | 0 | 0 | |
Righting reflex | 0 | +1 | +3 | |
Muscle tone | Limb tone | 0 | 0 | 0 |
Grip strength | 0 | 0 | 0 | |
Body sag | 0 | 0 | 0 | |
Body tone | 0 | −1 | −2 | |
Abdominal tone | 0 | −1 | −2 | |
Reflexes | Pinna | 0 | 0 | −4 |
Corneal | 0 | 0 | 0 | |
Ipsilateral Flexor Reflex | 0 | 0 | 0 | |
Autonomic function | Writhing | 0 | 0 | 0 |
Pupil size | 0 | 0 | 0 | |
Palpebral opening | 0 | −2 | −2 | |
Exophthalmus | 0 | 0 | 0 | |
Urination | 0 | 0 | 0 | |
Salivation | 0 | 0 | 0 | |
Piloerection | 0 | 0 | 0 | |
Hypothermia | 0 | 0 | 0 | |
Skin colour | 0 | 0 | 0 | |
Respiration rate | 0 | 0 | 0 |
