Table 7 Haematological and clinical chemistry parameters with significant differences compared to the control animals. Differences are not considered to be test item-related.

From: Toxicological testing of allogeneic secretome derived from peripheral mononuclear cells (APOSEC): a novel cell-free therapeutic agent in skin disease

Parameter

Group/Sex

mean value SD

Test day

Statistical significance

Reason

Reticulocytes (%)

4 f

4.15

0.68

25

p ≤ 0.01

A

Platelets (x103/µl)

4 m

1085.0

55.5

25

p ≤ 0.01

A

Eosinophilic

granulocytes

(absolute; x103/µl)

4 f

0.266

0.064

39

p ≤ 0.05

A

Thrombin time (s)

4 m

13.40

0.37

44

p ≤ 0.05

A

ALAT (U/L)

4 m

43.8

10.0

44

p ≤ 0.05

A

ASAT (U/L)

4 m

124.6

27.6

44

p ≤ 0.05

A

  1. m: male.
  2. f: female.
  3. A: the slight alteration in comparison to control animals is without any biological relevance.
  4. ALAT: alanine aminotransferase.
  5. ASAT: aspartate aminotransferase.
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