Figure 9
From: Evolution of folate biosynthesis and metabolism across algae and land plant lineages

Phylogenetic representation in the protein sequence space for DHPS domains. Non-linear mapping methods are designed to offer a configuration of points in this multidimensional space that is representative of the observed distances. With this method, axes become arbitrary and every rotation or symmetry is admissible. In this figure, the distance between two data points on the figure tends to display the distances between species. Links between points show the ML phylogenic tree presented in the Fig. 8. Blue branches: monofunctional enzyme, red branches: bifunctional enzyme. Brown letters, bikont cluster; brown letters in bold, the green lineage; black letters, unikont cluster. Abbreviations for genus names: Arab_thM, Arabidopsis thaliana Mitochondrial; Arab_thC, Arabidopsis thaliana Cytosolic; Popu_tri, Populus trichocarpa; Pisu_sat, Pisum sativum; Oryz_sat, Oryza sativa; Phys_pat, Physcomitrella patens; Chla_rei, Chlamydomonas reinhardtii; Ostr_tau, Ostreococcus tauri; Plas_yoe, Plasmodium yoelii; Plas_ber, Plasmodium berghei; Toxo_gon, Toxoplasma gondii; Neos_can, Neospora caninum; Cyan_mer, Cyanidioschyzon merolae; Phae_tri, Phaeodactylum tricornutum; Thal_pse, Thalassiosira pseudonana; Aura_lim, Aurantiochytrium limacinum; Phyt_soj, Phytophthora sojae; Aspe_fum, Aspergillus fumigatus; Aspe_ory, Aspergillus oryzae; Neur_cra, Neurospora crassa; Pneu_car, Pneumocystis carinii; Ashb_gos, Ashbya gossypii; Cand_gla, Candida glabrata; Bige_nat, Bigelowiella natans; Rick_gry, Rickettsiella grylli; Chla_pne, Chlamydia pneumonia; Rick_bel, Rickettsia bellii; Wolb_dro, Wolbachia Drosophila simulans; Fran_phi, Francisella philomiragia; Esch_col, Escherichia coli; Salm_typ, Salmonella typhi; Baci_sub, Bacillus subtilis; Stap_aur, Staphylococcus aureus; Syne_cho, Synechococcus sp.; Anab_var, Anabaena variabilis; Micr_cht, Microcoleus.