Figure 1 | Scientific Reports

Figure 1

From: Direct measurement of the mechanical properties of a chromatin analog and the epigenetic effects of para-sulphonato-calix[4]arene

Figure 1

Schematic representation of the set up for reconstituting chromatin and make mechanical epigenetic assay. (A) Scheme representation of histone and para-sulphonato-calix[4]arene SC4 with its given structure. (B) Setup for the SNT device immersed in the lateral opening of the channel of the microfluidic device. (C) Entering in the channel via the side opening, the captured DNA bundle between SNTs tips interact first with nucleosome for reconstituting chromatin and then assess the mechanical stress of epigenetic drugs.

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