Figure 5 | Scientific Reports

Figure 5

From: On resin click-chemistry-mediated synthesis of novel enkephalin analogues with potent anti-nociceptive activity

Figure 5

Effects induced by NOVA2 (N) and DPDPE (D) in the hot plate test in mice. In the left panel, the effects induced by i.c.v. administered NOVA2 and DPDPE at doses of 5 and 23 nmol are reported. In the right panel, the effects induced by i.v. administered NOVA2 and DPDPE at the dose of 23 μmol are reported. ** is for P < 0.01, *** is for P < 0.001 and **** is for P < 0.0001 comparing NOVA2 vs DPDPE at the same dose. N = 6–9.

Back to article page