Table 3 Sensitivities and specificities of individual quantitative MRI parameters [ms], relative changes in quantitative MRI parameters [%] and selected combinations thereof.

From: Detection of Early-Stage Degeneration in Human Articular Cartilage by Multiparametric MR Imaging Mapping of Tissue Functionality

 

Quantitative MRI parameters

Relative changes in quantitative MRI parameters

Selected combinations

T1

T1ρ

T2

T2*

T1Δ2.5

T1Δ5.0

T1ρΔ2.5

T1ρΔ5.0

T2Δ2.5

T2Δ5.0

T2*Δ2.5

T2*Δ5.0

T2 +T2*Δ5.0

T1ρ +T2*Δ5.0

T2 +T2Δ2.5 (*)

T1 +T2Δ2.5 (*)

T1 +T1Δ2.5

T1ρ +T1ρΔ2.5

T2 +T2Δ2.5

T2* +T2*Δ2.5

Sensitivity

0.630

0.810

0.852

0.630

0.741

0.741

0.667

0.619

0.704

0.667

0.593

0.778

0.967

0.958

0.600

0.444

0.904

0.937

0.956

0.849

Specificity

0.364

0.313

0.364

0.273

0.227

0.182

0.250

0.188

0.500

0.364

0.409

0.409

0.149

0.128

0.682

0.682

0.083

0.078

0.182

0.112

int [range, min; max]

638.9; 868.3

83.8; 116.6

35.2; 48.4

17.8; 26.2

−17.0; 1.9

−26.2; −0.3

−18.0; 33.3

−20.3; 32.6

−4.2; 12.6

−15.2; 9.8

−15.2; 9.9

−16.7; 20.7

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

deg [range, min; max]

<638.9; >868.3

<83.8; >116.6

<35.2; >48.4

<17.8; >26.2

<−17.0; >1.9

<−26.2; >−0.3

<−18.0; >33.3

<−20.3; >32.6

<−4.2; >12.6

<−15.2; >9.8

<−15.2; >9.9

<−16.7; >20.7

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

  1. Combined maximum sensitivities were calculated according to the believe the positive rule, while (*) indicates maximum specificity based on the believe the negative rule. Abbreviations as in Table 1.
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