Table 3 Candida-Staphylococcus polymicrobial biofilm inhibition by native MSNPs, PCN and PCN-MSNPs.

From: Phenazine-1-carboxamide functionalized mesoporous silica nanoparticles as antimicrobial coatings on silicone urethral catheters

Yeast strains

Biofilm inhibitory concentration (µM)

PCN

PCN-MSNPs

MSNPs

C. albicans MTCC 227 + S. aureus MTCC 96

105.23 ± 0.14

53.23 ± 0.10

—

C. albicans MTCC 227 + S. aureus MLS-16 MTCC 2940

119.98 ± 0.22

55.64 ± 0.24

—

  1. BIC: Biofilm inhibitory concentration is the least concentration of test compound at which OD600 difference or less than 10% of the mean of two positive growth readings. PCN: Phenazine-1-carboxamide; MSNPs: Mesoporous silica nanoparticles; PCN-MSNPs: PCN-functionalized MSNPs; “–”: No activity.
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