Table 1 Panel of CRC cell lines used in 3D cultures.

DLD1

Metastatic

C

MSI

APC^{l1417fs,R2166}, KRAS^G13D, PIK3CA^E545K;D549N, TP53^S241F

20

^{68,69,70,– 71}

SW620

Metastatic

C

MSS; CIN^pos46

APC^Q1338, KRAS^G12V, TP53^R273H;P309S

31

^{70,71,72,– 73}

HCT116

Primary

A

MSI

KRAS^G13D, PIK3CA^H1047R,

20–24

^{70, 71, 73, 74}

LS174T

Primary

C

MSI

KRAS^G12D, PIK3CA^H1047R,

32

^{70, 71, 75}

HT29

Primary

C

MSS

APC^E853;T1556fs, BRAF^V600E, PIK3CA^P449T, TP53^R273H,

20–24

^{70, 76}

Caco2

Primary

B

MSS; CIN^pos48

TP53

20–24

^{70, 77}

SW48

Primary

C

MSI

EGFR^G719S

31

^{70, 72, 78}