Table 3 Thyroid function according to different pathologic classifications.

From: The relationship between thyroid dysfunction and nephrotic syndrome: a clinicopathological study

 

MCD

MPGN

MsPGN

MN

FSGS

IgAN

Secondary

P#

N

110

7

9

98

15

27

51

—

Age (Year)

34.29 ± 16.17

38.86 ± 8.88

40.89 ± 15.09

47.85 ± 13.69*

41.64 ± 17.48

38.04 ± 15.31

42.8 ± 14.88

<0.001

Male (%)

55.5%

71.4%

33.3%

55.2%

45.5%

34.6%

60.8%

0.250

FT3 (pmol/L)

3.09 ± 1.06

3.07 ± 0.91

2.95 ± 0.97

3.91 ± 1.75*

3.66 ± 1.63

3.36 ± 1.17

3.24 ± 1.02

0.001

TT3 (nmol/L)

1.16 ± 0.49

0.53 ± 0.1

1.09 ± 0.39

1.49 ± 0.43*

1.27 ± 0.1

1.31 ± 0.17

1.45 ± 0.41

0.058

FT4 (pmol/L)

12.68 ± 3.22

12.92 ± 2.25

13.47 ± 4

13.68 ± 3.53*

14.51 ± 4.55

14.09 ± 3.67

13.59 ± 3.34

0.256

TT4 (nmol/L)

59.33 ± 21.24

44.61 ± 0.3

78.79 ± 22.78*

73.99 ± 22.61*

106.5 ± 0.2*

91.09 ± 14.05*

79.85 ± 29.38*

0.014

TSH (mU/L)

5.42 ± 5.29

3.31 ± 1.64

3.7 ± 2.59

4.36 ± 2.81

4.33 ± 3.44

5.38 ± 3.94

6.45 ± 13.63

0.571

RT3 (nmol/L)

0.27 ± 0.13

0.33 ± 0.1

0.43 ± 0.06

0.35 ± 0.19

0.29 ± 0.15

0.3 ± 0.1

0.3 ± 0.15

0.403

Thyroid subgroups

       

0.028

Normal Thyroid (%)

14.81%

28.57%

0.00%

23.00%

18.18%

23.08%

16.00%

 

Subclinical Hypothyroidism (%)

12.04%

14.29%

11.11%

28.00%

27.27%

23.08%

16.00%

 

Hypothyroidism (%)

37.04%

14.29%

22.22%

18.00%

9.09%

19.23%

30.00%

 

Low T3 (%)

19.44%

0.00%

33.33%

15.00%

18.18%

26.92%

30.00%

 

Low T4 (%)

0.93%

0.00%

0.00%

4.00%

0.00%

0.00%

0.00%

 

Low T3T4 (%)

15.74%

42.86%

33.33%

12.00%

27.27%

7.69%

8.00%

 
  1. Data are expressed as mean ± standard deviation (SD), median and interquartile range (IQR), or percent frequency, as appropriate.
  2. MN membranous nephropathy, MCD minimal-change disease, FSGS focal segmental glomerulosclerosis, MPGN membrane proliferative glomerulonephritis, MsPGN mesangial proliferative glomerulonephritis, secondary secondary reasons of nephrotic syndrome.
  3. #Comparison among groups. *P < 0.05, Comparison versus MCD group.