Table 4 Logistic regression analyses of 3-month mortality for 2-HB, 3-HB, lactate, citrate, and tyrosine.

From: Serum Concentrations of Citrate, Tyrosine, 2- and 3- Hydroxybutyrate are Associated with Increased 3-Month Mortality in Acute Heart Failure Patients

 

Unadjusted

Adjusteda

OR (95% CI)

p-Value

OR (95% CI)

p-Value

2-HB (µmol/L)

7.14 (1.73–33.50)

0.009

10.29 (1.78–74.18)

0.013

3-HB (µmol/L)

2.42 (1.32–4.58)

0.005

2.15 (1.06–4.50)

0.034

Lactate (µmol/L)

4.36 (1.52–13.57)

0.008

3.64 (1.01–14.92)

0.057

Citrate (µmol/L)

26.24 (5.89–139.62)

<0.001

11.74 (1.44–113.20)

0.026

Tyrosine (µmol/L)

24.48 (5.11–157.78)

<0.001

34.70 (4.49–386.70)

0.002

  1. aThe model was adjusted for age, sex, BMI, T2DM, NT-proBNP, GFR, MAP and LDL-cholesterol.
  2. Log-transformed values of the metabolite concentrations were used as covariates.
  3. The unadjusted analyses comprised data of 130 patients (32 events) and the adjusted analyses data of 122 patients (29 events).
  4. Significant results are depicted in bold.
  5. BMI, body mass index; 2-HB, 2-Hydroxybutyrate; 3-HB, 3-Hydroxybutyrate; CI, confidence interval; LDL, low-density lipoprotein; MAP, mean arterial pressure; NT-proBNP, N-terminal pro brain natriuretic peptide; OR, odds ratio.
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