Figure 5 | Scientific Reports

Figure 5

From: ATP-binding Cassette Transporters Substantially Reduce Estimates of ALDH-positive Cancer Cells based on Aldefluor and AldeRed588 Assays

Figure 5

Limiting dilution assays for assessment of functional stemness. Number of tumor-spheres formed 10 days after seeding 100 or 1,000 Aldefluor-negative or -positive CT26 cells selected in buffer containing DMSO vehicle (null), MK571, novobiocin or verapamil, or in AAB. Bars are mean ± SD of % relative to controls obtained from a single experiment with 5 samples per group. †P < 0.005, *P < 0.05, compared to wells seeded with identical numbers of Aldefluor-negative cells.

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