Table 2 Plasma concentrations of 21 free amino acids in patients and healthy controls (n = 295) from Bangladesh.
From: Amino acid derangements in adults with severe falciparum malaria
Name | Abbrev | Severe Malaria (n = 88) (µmol/L) | Uncomplicated Malaria (n = 71) (µmol/L) | SIRS/sepsis (n = 88) (µmol/L) | Healthy control (n = 48) (µmol/L) | ||||
|---|---|---|---|---|---|---|---|---|---|
Alanine | Ala | 549 | (350 to 858) | 178 | (10 to 407) | 445 | (343 to 622) | 625 | (413 to 784) |
Arginine | Arg | 43 | (33 to 51) | 32 | (24 to 44) | 36 | (28 to 45) | 75 | (59 to 85) |
Asparagine | Asn | 19.7 | (16.4 to 25.2) | 14.7 | (11.7 to 18.5) | 13.9 | (11.9 to 19) | 19.7 | (17 to 21.9) |
Citrulline | Cit | 7.4 | (6.9 to 8.2) | 6.7 | (6.4 to 7.4) | 8 | (6.9 to 9.1) | 11.4 | (10.1 to 13.3) |
Cysteine | Cys | 44 | (19 to 59) | 28 | (5 to 41) | 42 | (33 to 56) | 56 | (53 to 61) |
Glutamate | Gln | 200 | (175 to 252) | 190 | (148 to 228) | 208 | (175 to 255) | 259 | (239 to 284) |
Glutamine | Glu | 190 | (116 to 305) | 130 | (61 to 294) | 302 | (147 to 434) | 718 | (469 to 954) |
Glycine | Gly | 55 | (37 to 72) | 26 | (8 to 47) | 47 | (36 to 68) | 82 | (64 to 100) |
Glycine-Proline | Gly-Pro | 343 | (93 to 789) | 184 | (38 to 361) | 493 | (304 to 935) | 536 | (425 to 700) |
Histidine | His | 262 | (200 to 327) | 144 | (101 to 202) | 155 | (105 to 210) | 290 | (266 to 337) |
Hydroxyproline | Hyp | 8.3 | (6.5 to 10.8) | 5.9 | (5 to 6.9) | 5.5 | (5 to 6.4) | 7.7 | (6.8 to 8.9) |
Leucine | Leu | 57 | (49 to 72) | 38 | (24 to 53) | 48 | (37 to 63) | 51 | (45 to 64) |
Lysine | Lys | 1150 | (897 to 1410) | 814 | (580 to 1130) | 802 | (516 to 1148) | 1460 | (1265 to 1660) |
Methionine | Met | 20.2 | (18.1 to 22.5) | 19.4 | (18.1 to 21.8) | 18.5 | (17.3 to 19.7) | 19.7 | (19 to 20.7) |
Ornithine | Orn | 196 | (106 to 377) | 129 | (22 to 239) | 219 | (94 to 333) | 519 | (437 to 663) |
Phenylalanine | Phe | 85 | (65 to 109) | 57 | (49 to 70) | 52 | (40 to 68) | 37 | (33 to 40) |
Proline | Pro | 551 | (417 to 696) | 277 | (128 to 443) | 376 | (274 to 477) | 540 | (455 to 594) |
Serine | Ser | 27.5 | (20.8 to 34.4) | 24.1 | (17.9 to 33.1) | 26.6 | (19 to 33.3) | 42 | (35.5 to 48) |
Tryptophan | Trp | 64 | (27 to 136) | 36 | (0 to 107) | 26 | (0 to 82) | 266 | (235 to 300) |
Tyrosine | Tyr | 67 | (43 to 98) | 34 | (19 to 63) | 57 | (41 to 76) | 91 | (83 to 107) |
Valine | Val | 790 | (603 to 968) | 387 | (128 to 611) | 579 | (446 to 799) | 704 | (524 to 936) |
Total PFAA (mmol/L) | 4.9 | (3.9 to 6.2) | 2.9 | (1.9 to 3.7) | 4.4 | (3.3 to 5.6) | 6.4 | (5.4 to 7.4) | |
