Figure 1

Ischemic stroke increases IL-37 in the plasma level of humans and mice. (a) Circulating level IL-37 protein is shown for control subjects (n = 24) and patients 3 days after an ischemic stroke (n = 55). (b) IL-37 protein abundance is shown for IL-37tg mice at 24 h after either sham surgery (n = 8) or ischemic stroke (n = 23). Data are presented as mean ± S.E.M.; *P < 0.05, Welch’s t-test.