Figure 6
From: TGFβ-induced cytoskeletal remodeling mediates elevation of cell stiffness and invasiveness in NSCLC
Gene Set Variation Analysis (GSVA) on the longitudinal gene expression data in the H1975 cells upon stimulation with growth factors TGFβ and HGF. The heatmap depicts the average GSVA enrichment scores at 0.5, 24 and 48 hours after TGFβ (A) and HGF (B) stimulation for time matched (n = 3). Gene sets have been taken from the epithelial-to-mesenchymal transition RT2 Profiler™ PCR Arrays by QIAGEN and are provided as Supplementary Table S1. Stars indicate a significant differential GSVA enrichment score according to a moderated t-test (FDR corrected p-value < 0.05). Rows have been clustered according to their Euclidean distance using complete linkage.
