Figure 2
From: The role of membrane excitability in pancreatic β-cell glucotoxicity
Islet Morphology. (a) Representative picture of pancreatic islets from KATP-WT or genetically altered mice 9 days after incubation in low or high glucose. (b) Quantification of mean gray values (A.U) for islet translucency on KATP-WT (black), KATP-KO (red) or KATP-GOF (green) islets chronically incubated in low- or high-glucose. n = 3 experiments from 9 independent mice, experiments were done in triplicates. Significant differences *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001 under the same condition; non-significant differences are not indicated in the figure. (c) Quantification of islet area (mm2) on KATP-WT (black), KATP-KO (red) or KATP-GOF (green) islets chronically incubated in low- or high-glucose. n = 3 experiments from 9 independent mice, experiments were done in triplicates.
