Table 1 Effect of sub-chronic administration of QTC-4-MeOBnE (0.1 and 1 mg/kg) for 20 days in toxicological parameters in mice.

From: Rational design, cognition and neuropathology evaluation of QTC-4-MeOBnE in a streptozotocin-induced mouse model of sporadic Alzheimer’s disease

 

Groups

Control

QTC-4-MeOBnE 0.1 mg/kg

QTC-4-MeOBnE 1 mg/kg

AST (U/l)

109.20 ± 15.81

120.21 ± 15.54

110.30 ± 10.27

ALT (U/l)

41.00 ± 3.78

34.20 ± 0.48

41.00 ± 3.78

Urea (mg/dl)

52.08 ± 5.03

44.01 ± 2.83

57.65 ± 4.38

Creatinine (mg/dl)

1.03 ± 0.11

1.01 ± 0.06

1.05 ± 0.07

  1. ALT: alanine aminotransferase; AST: aspartate aminotransferase.
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