Figure 6 | Scientific Reports

Figure 6

From: Integration of bilateral nociceptive inputs tunes spinal and cerebral responses

Figure 6

Source estimation of increased high gamma oscillations during bilateral stimulation. Time courses of high gamma oscillations induced by bilateral stimulation were compared to those induced by unilateral stimulation, using a voxelwise two-tailed paired t-test on time-frequency source space at 82 Hz. The contrast revealed sources of increased high gamma oscillations in the following regions: (a) Lateral prefrontal cortex bilaterally, maximally over the left DLPFC (102–162 ms). Pre-motor cortex bilaterally (102–130 ms). (b) Foot region of primary somatosensory cortex (SI) bilaterally (114–124 ms). Medial prefrontal cortex bilaterally (102–160 ms). (c) Posterior part of ACC extending to the anterior MCC and cingulomotor area bilaterally (130–158 ms). Positive and negative relationships are depicted by warm and cold colors, respectively. Whole-brain t-maps were thresholded at p < 0.05, false discovery rate corrected for the whole brain.

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