Figure 2 | Scientific Reports

Figure 2

From: The activity of the saponin ginsenoside Rh2 is enhanced by the interaction with membrane sphingomyelin but depressed by cholesterol

Figure 2

Rh2 adsorbs to a higher extent with eSM and DOPC than with Chol and ePC monolayers. Adsorption kinetics recorded at 25 °C of Rh2 on pure lipids (eSM (black), Chol (grey), ePC (white), DOPC (dotted line)). (A) Surface pressure – time (Π – t) curves for pure lipid monolayers at 30 ± 2 mN/m initial surface pressure recorded directly after the injection into the buffer subphase of Rh2 at the final concentration of 10 µM. (B) ΔΠ is the difference between the final and initial surface pressures. The curves are representative of three independent experiments and histogram data are means of these triplicated assays. One-way ANOVA with Bonferroni’s multiple comparison post test. **p < 0.01; ***p < 0.001.

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