Figure 5
Comparison of the degree of IFTA from histopathology of all mice, presented as individual points, against a simplified ESS spectral feature chosen by inspection (the relative areas under the curve of the spectra from 350 to 450 nm). IFTA assessment of the stained kidney slides was performed by an expert nephropathologist, and is expressed as a percentage of total kidney area that was affected. Data are displayed for all time-points of the UUO model, together with the data of the AD model (at 14 days). Controls (untreated) for both models are represented by the triangles (and evidenced no significant difference between the two strains used in the AD model). Computed correlation coefficient: r = 0.85; confidence interval [0.73. 0.92]; p-value, p ≪ 0.05.
