Table 2 Luciferase expression levels from naïve heart, three native hearts, and three allografts.
From: A normothermic ex vivo organ perfusion delivery method for cardiac transplantation gene therapy
Heart Region | Naïve heart RLU/mg protein | Native heart (n = 3) RLU/mg protein | Allograft 1 RLU/mg protein | Allograft 2 RLU/mg protein | Allograft 3 RLU/mg protein |
|---|---|---|---|---|---|
Left ventricle sections | |||||
Atrioventricular junction | 104.4 ± 21.4 | 67.4 ± 49.9 | 1630.0 ± 368.4 | 186132.8 ± 4412.1 | 91204.0 ± 18571 |
Middle | 104.4 ± 30.0 | 60.7 ± 36.8 | 3908.0 ± 382.8 | 145482.6 ± 782.1 | 659463.0 ± 9544.59 |
Juxta apex | 131.1 ± 36.7 | 287.4 ± 185.1 | 28053.0 ± 594.2 | 643349.4 ± 6362.2 | 667541.2 ± 5044.4 |
Apex | 115.5 ± 45.3 | 747.3 ± 853.2 | 14560.1 ± 1146.1 | 788750.4 ± 33528.2 | 1437765.5 ± 8713.1 |
Right ventricle sections | |||||
Atrioventricular junction | 771.1 ± 1049.7 | 80.5 ± 107.6 | 12226.9 ± 1065.4 | 12708147.5 ± 283221.4 | 316520.9 ± 18900.4 |
Middle | 71.1 ± 33.5 | 43.3 ± 23.0 | 2293.4 ± 280.9 | 740159.9 ± 26207.5 | 2366458.6 ± 22373.2 |
Juxta apex | 126.6 ± 33.3 | 81.3 ± 18.0 | 27987.2 ± 4801.6 | 2672829.0 ± 33050.2 | 392790.5 ± 6131.9 |
Apex | 137.7 ± 36.7 | 456.7 ± 618.4 | 1994.4 ± 132.1 | 782733.2 ± 6536.0 | 9099456.5 ± 73751.5 |
Ventriclular septum sections | |||||
Atrioventricular junction | 186.6 ± 103.7 | 66.6 ± 51.5 | 13835.0 ± 749.4 | 635594.0 ± 13516.8 | 745212.5 ± 17625.5 |
Middle | 122.2 ± 7.6 | 44.6 ± 51.1 | 8495.7 ± 278.6 | 163896.0 ± 2359.3 | 449768.9 ± 9206.1 |
Juxta apex | 111.1 ± 10.1 | 187.6 ± 245.7 | 36349.7 ± 1094.9 | 2898714.2 ± 94065.9 | 1668397.2 ± 21115.1 |
Apex | 148.8 ± 30.0 | 62.3 ± 61.2 | 2998.3 ± 435.3 | 93257.7 ± 2506.8 | 2434775.2 ± 58712.1 |
