Table 2 Relationships of TREML4 polymorphisms with coronary artery lesion extension in CAD patients.

From: TREML4 mRNA Expression and Polymorphisms in Blood Leukocytes are Associated with Atherosclerotic Lesion Extension in Coronary Artery Disease

Polymorphism

All

Extension of coronary artery lesion

p

Without

Low

Intermediate

Major

rs2803495 A/G

N = 136

N = 33

N = 39

N = 40

N = 22

Genotypes, %

AA

77.9 (106)

78.8 (26)

82.1 (32)

75.6 (31)

73.9 (17)

0.813

(Codominant)

AG

20.6 (28)

21.2 (7)

17.9 (7)

22.0 (9)

21.7 (5)

 

GG

1.5 (2)

0

0

2.4 (1)

4.3 (1)

(Dominant)

AA

77.9 (106)

78.8 (26)

82.1 (32)

75.6 (31)

73.9 (17)

0.863

 

AG + GG

22.1 (30)

21.2 (7)

17.9 (7)

24.4 (10)

26.1 (6)

Alleles, %

A

88.2 (134)

89.4

91.0

86.6

84.8

0.702

 

G

11.8 (2)

10.6

9.0

13.4

15.2

rs2803496 C/T

N = 134

N = 31

N = 39

N = 40

N = 23

Genotypes, %

TT

76.9 (103)

83.9 (26)

71.8 (28)

80.5 (33)

69.6 (16)

0.526

(Codominant)

CT

22.4 (30)

16.1 (5)

28.2 (11)

17.1 (7)

30.4 (7)

 

CC

0.7 (1)

0

0

2.4 (1)

0

(Dominant)

TT

76.9 (103)

83.9 (26)

71.8 (28)

80.5 (33)

69.6 (16)

0.492

 

CT + CC

23.1 (31)

16.1 (5)

28.2 (11)

19.5 (8)

30.4 (7)

Alleles, %

T

88.1 (133)

91.9

85.9

89.0

84.8

0.620

 

C

11.9 (1)

8.1

14.1

11.0

15.2

  1. Numbers of subjects are indicated in parentheses. Frequencies were compared by the Chi-Square test. p-Values refer to comparisons among genotype frequencies of the different models and among allelic frequencies. For less than 10% of all samples, the genotype could not be determined. ‘Without’, Friesinger index 0; ‘Low’, Friesinger index 1–5; ‘Intermediate’, Friesinger index 6–10; ‘Major’, Friesinger index 11–15.
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