Figure 1
From: A 3D bioprinter platform for mechanistic analysis of tumoroids and chimeric mammary organoids

3D Bioprinting of consistent MCF-7 and MDA-MB-468 tumoroids. (a1–3) MCF-7 cell deposits (40 cells/deposit) spaced 300 µm apart at 1, 14, and 21 days post-printing. (b1–b3) MDA-MB-468 cell deposits (40 cells/deposit) spaced 300 µm apart at 1, 14, and 21 days post-printing. (c) Example of reliable printed array of GFP + MCF-7 tumoroids 21 days post-print with distinct structures. (d) Example of a linear array MDA-MB-468 tumor organoids at 21 days with all the multiple print sites fused into a single structure. (e,f) H&E stains of (e) MCF-7 and (f) MDA-MB-468 tumor organoids at 21 days. (Scale bars: a and b = 1 mm; c and d = 500 µm; e and f = 150 µm).