Table 1 Correlation between IQGAP1 expression and clinicopathological variables in patients with PDAC.
Variables | Number | IQGAP1L (%) | IQGAP1H (%) | P* |
|---|---|---|---|---|
Sex | ||||
Male | 54 | 20 (37.0) | 34 (63.0) | 0.521 |
Female | 33 | 10 (30.3) | 23 (69.7) | |
Age a | ||||
≤61 | 44 | 16 (36.4) | 28 (63.6) | 0.709 |
>61 | 43 | 14 (32.6) | 29 (67.4) | |
Tumor location | ||||
Pancreatic head | 56 | 16 (28.6) | 40 (71.4) | 0.119 |
Non-head | 31 | 14 (45.2) | 17 (54.8) | |
Tumor size (cm) | ||||
<4 | 26 | 5 (19.2) | 21 (80.8) | 0.051 |
≥4 | 61 | 25 (41.0) | 36 (59.0) | |
Histological differentiation | ||||
Well-moderate | 66 | 27 (40.9) | 39 (59.1) | 0.034b |
Poor | 21 | 3 (14.3) | 18 (85.7) | |
TNM stage | ||||
I + II | 86 | 30 (34.9) | 56 (65.1) | 1b |
III + IV | 1 | 0 (0) | 1 (100) | |
T classification | 0.397 | |||
T1/T2 | 68 | 25 (36.8) | 43 (63.2) | |
T3 | 19 | 5 (26.3) | 14 (73.7) | |
N classification | ||||
N0 | 47 | 21 (44.7) | 26 (55.3) | 0.030 |
N1 | 40 | 9 (22.5) | 31 (77.5) | |
M classification | ||||
M0 | 86 | 30 (34.9) | 56 (65.1) | 1b |
M1 | 1 | 0 (0) | 1 (100) | |
Perineural invasion | ||||
Present | 35 | 10 (28.6) | 25 (71.4) | 0.341 |
Absent | 52 | 20 (38.5) | 32 (61.5) | |
