Figure 6
Representative images at baseline and 24 hours after sham or transient (60 minute) MCAo procedure. Microglia in the resting state have ramified processes, as seen in both baseline conditions (Baseline a,b) and in the sham injured mouse (Sham, b). When microglia become activated, their processes retract and the cells often exhibit a brushy or ameboid morphology (24 hr post-I/R, a). Insets are enlarged, representative images of microglia (caret) morphology. Images are z-projections of 5 × 1 µm optical slices. Scale bar denotes 10 µm, inset scale bar denotes 5 µm.
