Figure 9

hrGRIN lens system implantation. (a) An assembled hrGRIN microlens is loaded into a cannula holder and stereotaxically aligned for implantation. (b) The top of the cannula holder is angled 15° away from the midline to ensure the system lays flat on the skull and then it is slowly lowered at a rate of 0.1 mm/min to minimize damage from implantation. (c) RelyX Aplicap (3M) dental adhesive is applied under the coverslip and around the skull after implantation. Once the adhesive has cured (~20 minutes), the cannula holder is removed.