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Figure 1

From: Increased prefrontal cortex interleukin-2 protein levels and shift in the peripheral T cell population in progressive supranuclear palsy patients

Figure 1

Interleukin-2 (IL-2) and glycogen synthase kinase 3 beta (GSK3B) levels. (A) IL-2 protein levels in progressive supranuclear palsy (PSP) patients normalized to normal control (NC) levels. Protein levels were measured using two commercial assays based on Luminex or MSD technology. Filled symbols mark male subjects, open symbols mark female subjects. (B) mRNA levels of GSK3B. Expression levels normalized to the reference genes ubiquitin-conjugating enzyme 2D2 (UBE2D2), ribosomal protein 13a (RPL13A) and DNA topoisomerase 1 (TOP1). Data presented as mean ± SEM. *p < 0.050; **p < 0.010. (C) Immunofluorescent stainings of IL-2 (red), and NeuN (green) or (D) GFAP (green). Nuclei are stained with DAPI (blue). Scale bars: 20 µm, 100X magnification.

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