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Figure 1

From: Systems Pharmacogenomic Landscape of Drug Similarities from LINCS data: Drug Association Networks

Figure 1

(A) Conceptual connection between genotype space, phenotype space and compound space containing DANs. (B) Multifacturial experimental space of the LINCS data. (C) For our analysis we study 7 different DANs. (D) Overview of the connstruction of a DAN. The figure shows the gene expression profile signature of drugs and small molecule compounds from LINCS L1000 subset. Representation of the use of drug-feature matrices of different types to calculate drug connections using Jaccard Index (JI).

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