Figure 4
From: Systems Pharmacogenomic Landscape of Drug Similarities from LINCS data: Drug Association Networks
Significant interactions between drugs with the same ATC classes. Here the notation, e.g., L means L − L (x-axis) (similar for other ATC codes) and their corresponding Jaccard Indices. (A) Number of significant interactions between the same ATC codes (i.e two drugs with the same ATC class) for the networks Napproved (right) and Nall (left). The boxplots show the distribution of JI of all significant interactions of drugs which are annotated with the same ATC codes of Napproved (right) and Nall (left). (B) Results for the 5 networks NMCF7, NVCAP, NPC3, NA549 and NA375. Shown results are similar as for (A). The colored y-axis label indicate the type of network analysed.
