Table 1 Contingency table summarizing the gene regulation profiles Ri and Rj treated by drug Dk and Dl.

From: Systems Pharmacogenomic Landscape of Drug Similarities from LINCS data: Drug Association Networks

Di↓/Dj→

−1 (down)

0 (no change)

1 (up)

−1 (down)

n 11

n 12

n 13

(no change)

n 21

n 22

n 23

(up)

n 31

n 32

n 33

  1. Here nkl are integer numbers giving the common genes in the categories k, l ∈ {up, nochange, down}.