Table 3 Spearman correlations between gestational age and erythrocyte n-6 and n-3 polyunsaturated fatty acids of preterm infants with or without retinopathy of prematurity.

From: Alteration of erythrocyte membrane polyunsaturated fatty acids in preterm newborns with retinopathy of prematurity

 

No-ROP

n = 25

ROP

n = 27

rSpearman

P-value

rSpearman

P-value

n-6 PUFAs

C18:2n-6 (linoleic acid, LA)

−0.354

0.0817

0.230

0.2467

C20:4n-6 (arachidonic acid, AA)

−0.300

0.1447

−0.012

0.9511

C22:4n-6

−0.315

0.1251

0.026

0.8958

C22:5n-6 (n-6 docosapentaenoic acid, n-6 DPA)

−0.321

0.1169

−0.1233

0.5402

n-3 PUFAs

C18:3n-3 (α-linolenic acid, ALA)

0.061

0.7693

−0.457

0.0163

C20:5n-3 (eicosapentaenoic acid, EPA)

−0.582

0.0022

0.062

0.7577

C22:5n-3 (n-3 docosapentaenoic acid, n-3 DPA)

−0.367

0.0712

0.009

0.9607

C22:6n-3 (docosahexaenoic acid, DHA)

−0.396

0.0500

−0.176

0.3774

ratios

C18:2n-6/C18:3n-3 (LA/ALA)

−0.216

0.2978

0.3414

0.0813

C20:4n-6/C20:5n-3 (AA/EPA)

−0.202

0.3307

0.090

0.6540

C22:4n-6/C22:5n-3 (C22:4n-6/n-3 DPA)

−0.061

0.7710

0.251

0.2065

C22:5n-6/C22:6n-3 (n-6 DPA/DHA)

0.422

0.0356

−0.055

0.7837

C20:4n-6/C22:6n-3 (AA/DHA)

−0.188

0.3668

0.595

0.0010

  1. ROP: retinopathy of prematurity; PUFA: polyunsaturated fatty acids; LA: linoleic acid, ALA; α-linolenic acid; n-6 DPA: AA: arachidonic acid; EPA: eicosapentaenoic acid; n-6 DPA: n-6 docosapentaenoic acid; n-3 DPA: n-3 docosapentaenoic acid; DHA: docosahexaenoic acid.
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