Table 1 Clinical Characteristics.
All Infants | Infants without Sepsis, Necrotizing Enterocolitis, or Intestinal Perforation | |||
|---|---|---|---|---|
Appropriate Growth (n = 22) | Growth Failure (n = 36) | Appropriate Growth (n = 20) | Growth Failure (n = 21) | |
Gestational age (wks), med (IQR) | 27 (26, 27) | 25 (24, 26)* | 27 (26, 27) | 26 (25, 27)* |
Birth weight (g), med (IQR) | 873 (816, 1063) | 753 (640, 845)* | 925 (820, 1073) | 755 (640, 860)* |
Race, n (%) | ||||
Asian | 3 (14) | 3 (8) | 3 (15) | 1 (5) |
Black or African American | 13 (59) | 16 (44) | 11 (55) | 10 (48) |
White | 5 (23) | 17 (47) | 5 (25) | 10 (48) |
Unknown or not reported | 1 (5) | 0 (0) | 1 (5) | 0 (0) |
Female sex, n (%) | 12 (55) | 18 (50) | 10 (50) | 10 (48) |
Multiple gestation, n (%) | 8 (36) | 9 (25) | 8 (40) | 5 (24) |
Antenatal steroids, n (%) | 22 (100) | 34 (94) | 20 (100) | 20 (95) |
Antenatal antibiotics, n (%) | 16 (73) | 24 (67) | 15 (75) | 12 (57) |
C-section delivery, n (%) | 17 (77) | 27 (75) | 15 (75) | 15 (71) |
Growth outcomes | ||||
Weight percentile, med (IQR) | 10 (6, 14) | <1 (<1, 1)* | 10 (7, 16) | <1 (<1, 1)* |
Length percentile, med (IQR) | 7 (2, 11) | <1 (<1, <1)* | 7 (3, 11) | <1 (<1, <1)* |
Head circumference, med (IQR) | 25 (9, 41) | 2 (<1, 6)* | 26 (15, 44) | 2 (<1, 6)* |
Morbidities and Therapies | ||||
Late-onset sepsis, n (%) | 1 (5) | 6 (17) | 0 (0) | 0 (0) |
Spontaneous intestinal perforation, n (%) | 0 (0) | 6 (17) | 0 (0) | 0 (0) |
Medical necrotizing enterocolitis, n (%) | 1 (5) | 3 (8) | 0 (0) | 0 (0) |
Surgical necrotizing enterocolitis, n (%) | 0 (0) | 4 (11) | 0 (0) | 0 (0) |
Severe intraventricular hemorrhage, n (%) | 2 (9) | 3 (8) | 2 (10) | 1 (5) |
Severe retinopathy of prematurity, n (%) | 2 (9) | 13 (36)* | 2 (10) | 7 (33) |
Ligation of patent ductus arteriosus, n (%) | 2 (9) | 9 (25) | 2 (10) | 4 (19) |
First day enteral feeds, med (IQR) | 4 (3, 5) | 5 (4, 9) | 4 (3, 5) | 5 (3, 10) |
Day of first full feeds sample collection, med (IQR) | 28 (20, 38) | 42 (30, 55)* | 26 (19, 38) | 35 (25, 42) |
Initial days antibiotics, med (IQR) | 2 (2, 7) | 2 (2, 6) | 2 (2, 7) | 2 (2, 6) |
Total days antibiotics, med (IQR) | 15 (8, 20) | 20 (12, 37) | 12 (8, 19) | 14 (11, 25) |
Initial days mechanical ventilation, med (IQR) | 3 (1, 6) | 9 (2, 19)* | 3 (1, 5) | 11 (2, 18)* |
Total days mechanical ventilation, med (IQR) | 4 (2, 12) | 19 (8, 27)* | 3 (2, 11) | 16 (4, 22)* |
