Figure 3

Heatmap with the pseudocolor scale underneath, of the differentially expressed miRNAs among the 40 samples. Unsupervised hierarchical clustering is used to order samples and miRNAs, the log2-transformed microarray signal was considered. The sample tree with optimized leaf-ordering is drawn using Euclidean distances and average linkages for cluster-to-cluster distance. The six major clusters are identified by different colors: Cluster 1 (red), cluster 2 (blue), cluster 3 (green), cluster 4 (yellow), cluster 5 (orange), cluster 6 (light blue).