Table 4 Gestational age groups and interstitial glucose parameters following hypoglycemia.

From: Factors influencing glycaemic stability after neonatal hypoglycaemia and relationship to neurodevelopmental outcome

 

Total

Gestational age groups (weeks)

32–34

35–36

≥37

Number of 6-hour epochs (babies)

201 (139)

14 (11)

71 (49)

116 (70)

Blood glucose at the onset of the epoch**

2.2 (0.3)

2.3 [2.1; 2.5]

1.9 (0.7)b

2.1 [1.7; 2.2]

2.3 (0.2)a

2.3 [2.1; 2.4]

2.2 (0.3)a

2.3 [2.1; 2.5]

Number of blood glucose concentrations <2.6 mmol/l per epoch

1 [1; 2]

1 [1; 2]

1 [1; 2]

1 [1; 2]

Hours to maximum IG*

3.3 (1.7)

3.0 [2.0; 4.9]

2.4 (1.1)

2.2 [1.7; 2.5]

3.7 (1.8)

3.5 [2.2; 5.6]

3.2 (1.6)

3.0 [2.0; 4.6]

Average IG**

3.2 (0.6)

3.1 [2.8; 3.5]

3.7 (0.9)b

3.7 [3.0; 4.4]

3.3 (0.6)a

3.2 [2.9; 3.6]

3.1 (0.6)a

3.1 [2.8; 3.4]

Maximum IG*

4.1 (1.1)

3.7 [3.4;4.5]

5.0 (1.6)b

4.8 [3.7; 5.6]

4.1 (1.1)a

3.7 [3.4; 4.5]

4.0 (1.0)a

3.7 [3.4; 4.2]

Minimum IG*

2.2 (0.4)

2.2 [2.0;2.4]

2.0 (0.7)

2.2 [1.7; 2.5]

2.2 (0.3)

2.3 [2.1; 2.4]

2.2 (0.3)

2.2 [2.0; 2.4]

IG range*

1.9 (1.2)

1.6 [1.2;2.2]

3.1 (1.7)b

2.5 [2.0; 4.3]

1.9 (1.1)a

1.6 [1.2; 2.2]

1.8 (1.1)a

1.6 [1.1; 2.1]

Proportion IG outside central band of 3-4 mmol/l

0.57 (0.28)

0.61 [0.35;0.77]

0.66 (0.27)

0.73 [0.46; 0.85]

0.55 (0.29)

0.58 [0.27; 0.82]

0.58 (0.28)

0.61 [0.37; 0.76]

Duration (hours) IG <2.6 mmol/l

1.32 (1.23)

0.88 [0.41;1.76]

1.06 (1.47)

0.52 [0.32; 1.34]

1.13 (0.96)

0.87 [0.41; 1.52]

1.47 (1.33)

1.04 [0.41; 2.04]

  1. Data are number, median [interquartile range] or mean (standard deviation). Glucose concentrations are expressed as mmol/l. IG, interstitial glucose concentration. *P < 0.05, **P < 0.01 for comparisons among gestational age groups; letters indicate pairwise comparisons (Dunnett adjustment, ≥37 weeks as referent).