Table 5 Effect of feeding and treatment on interstitial glucose parameters in 6-hour epochs following hypoglycemia.

Number of 6-hours epochs (babies)^†

30 (25)

39 (23)

44 (32)

38 (29)

36 (19)

Blood glucose at the onset of the epoch

2.3 (0.2)^a

2.4 [2.3; 2.5]

2.3 (0.3)^a,b

2.4 [2.1; 2.5]

2.3 (0.3)^a,b

2.3 [2.1; 2.5]

2.2 (0.3)^a,b

2.3 [2.1; 2.5]

2.1 (0.4)^b

2.2 [2.0; 2.4]

Number of blood glucose concentrations <2.6 mmol/l per epoch

1 [1; 1]

1 [1; 2]

1 [1; 2]

1 [1; 2]

2 [1; 2]

Hours to maximum IG

3.5 (1.8)

3.0 [2.1; 5.3]

3.4 (1.6)

3.1 [2.2; 4.8]

3.0 (1.4)

2.7 [2.0; 4.1]

3.7 (1.8)

4.1 [2.2; 5.5]

3.5 (1.8)

3.5 [2.0; 5.3]

Average IG*

3.0 (0.3)

2.9 [2.8; 3.2]

3.1 (0.5)

3.0 [2.7; 3.3]

3.2 (0.5)

3.2 [2.8; 3.6]

3.5 (0.5)

3.4 [3.0; 3.6]

3.4 (0.9)

3.2 [2.8; 3.6]

Maximum IG^***

3.5 (0.4)^a

3.4 [3.2; 3.6]

3.8 (1.0)^a,b

3.6 [3.3; 4.2]

3.9 (0.7)^a,b

3.7 [3.4; 4.3]

4.2 (0.8)^b,c

4.0 [3.7; 4.5]

4.6 (1.6)^c

4.0 [3.5; 5.5]

Minimum IG*

2.3 (0.2)^a

2.3 [2.1; 2.4]

2.2 (0.3)^a,b

2.2 [1.9; 2.4]

2.2 (0.3)^a

2.2 [2.1; 2.5]

2.2 (0.3)^a,b

2.2 [2.1; 2.4]

2.0 (0.4)^b

2.2 [1.9; 2.3]

IG range^***

1.2 (0.5)^a

1.1 [0.8; 1.4]

1.6 (1.0)^a,b

1.3 [1.1; 1.9]

1.6 (0.7)^a,b

1.5 [1.1; 1.9]

2.0 (0.9)^b,c

1.8 [1.5; 2.4]

2.6 (1.6)^c

1.9 [1.4; 3.3]

Proportion IG outside central band of 3–4 mmol/l

0.54 (0.31)

0.57 [0.22; 0.81]

0.59 (0.26)

0.60 [0.40; 0.77]

0.51 (0.27)

0.55 [0.27; 0.72]

0.51 (0.28)

0.49 [0.27; 0.76]

0.68 (0.28)

0.75 [0.51; 0.92]

Duration (hours) IG <2.6 mmol/l*

1.00 (0.81)

0.64 [0.41; 1.30]

1.37 (1.12)

1.14 [0.49; 1.92]

1.17 (1.13)

0.72 [0.36; 1.50]

1.24 (1.15)

0.87 [0.41; 1.38]

1.91 (1.54)

1.43 [0.75; 2.80]