Table 2 Reason for premature discontinuation or switch of ADP-blocker therapy, Drug intolerance entails dyspnea, allergy, and rhythm disorder.

From: Incidence, predictors, and prognosis of premature discontinuation or switch of prasugrel or ticagrelor: the ATLANTIS - SWITCH study

ADP Blocker

Reason to stop or switch ADP blocker

P-Value (overall)

Major surgery

Patients decision of unknown reason

Physician decision of unknown reason

OAC (+ASS)

Any bleeding

Drug intolerance

Ticagrelor n = 41 (15.9%)

0.530

4 (9.8)

10 (24.4)

5 (12.2)

10 (24.4)

4 (9.8)

8 (19.5)

Prasugrel n = 29 (9.2%)

 

1 (3.4)

12 (41.4)

2 (6.9)

7 (24.1)

4 (13.8)

3 (10.3)

  1. Any bleeding entails TIMI minimal, minor, or major events. P > 0.05 for comparisons between prasugrel and ticagrelor groups.
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