Table 1 Descriptive (mean (95% CI)) and comparative statistics of each ROI pair in each cohort for the uCP vs. TD comparison.

From: Influence of the corticospinal tract wiring pattern on sensorimotor functional connectivity and clinical correlates of upper limb function in unilateral cerebral palsy

 

TD cohort (n = 60)

uCP cohort (n = 26)

Wilk’s Lambda (p)

F (p)

group*connection

main effect group

Intra functional connectivity non-dominant hemisphere

0.98 (0.47)

1.33 (0.25)

M1-PMd

0.33 (0.05)

0.33 (0.09)

  

M1-PMv

0.03 (0.03)

0.09 (0.05)

  

M1-S1

0.69 (0.06)

0.73 (0.10)

  

Intra functional connectivity dominant hemisphere

0.97 (0.32)

2.73 (0.10)

M1-PMd

0.30 (0.06)

0.39 (0.11)

  

M1-PMv

0.03 (0.03)

0.14 (0.07)

  

M1-S1

0.87 (0.07)

0.85 (0.14)

  

Inter functional connectivity Non-dom → Dom

0.92 (0.07)

0.12 (0.73)

M1-PMd

0.19 (0.05)

0.27 (0.08)

  

M1-PMv

0.05 (0.03)

0.09 (0.06)

  

M1-S1

0.40 (0.06)

0.34 (0.07)

  

M1-SMA

0.32 (0.06)

0.30 (0.09)

  

Inter functional connectivity Dom → Non-dom

0.94 (0.14)

0.04 (0.85)

M1-PMd

0.22 (0.04)

0.25 (0.07)

  

M1-PMv

0.01 (0.03)

0.09 (0.08)

  

M1-S1

0.38 (0.06)

0.35 (0.07)

  

M1-SMA

0.29 (0.06)

0.23 (0.07)

  

M1-M1

0.47 (0.07)

0.47 (0.09)

 

0.00 (0.99)

  1. TD, typically developing; uCP, unilateral cerebral palsy; CST, corticospinal tract; M1, primary motor cortex; PMd, dorsal stream of the premotor cortex; PMv, ventral stream of the premotor cortex; S1, primary sensory cortex; SMA, supplementary motor area.