Table 3 Differences in connectivity pattern from non-dominant M1 to other brain regions.

From: Influence of the corticospinal tract wiring pattern on sensorimotor functional connectivity and clinical correlates of upper limb function in unilateral cerebral palsy

 

Cluster #

Location

Direction

Coordinates (x, y, z)

p-unc

p-FDR corrected

Cluster size

Seed on non-dominant M1

TD vs. uCP

1

Occipital lobe (non-dominant side)

TD > uCP

−11, −97, +31

<0.001

<0.001

8684

2

Occipital lobe (dominant side)

TD > uCP

+27, −101, +16

<0.001

<0.001

8109

3

Temporal pole, insular cortex (non-dominant side)

uCP > TD

−53, +16, −14

0.001

0.01

2804

TD vs. CST wiring

1

Occipital lobe (non-dominant side)

TD > contra

TD > ipsi

TD > bilat

−26, −95, +10

<0.001

<0.001

7273

2

Occipital lobe (dominant side)

TD > contra

TD > ipsi

TD > bilat

Ipsi > bilat

+10, −95, +28

<0.001

<0.001

7140

Seed on dominant M1

TD vs. uCP

None

      

TD vs. CST wiring

1

Occipital lobe (non-dominant side)

TD > contra

TD > bilat

Ipsi > bilat

−17, −95, +16

<0.001

<0.001

3585

2

Occipital lobe (dominant side)

TD > contra

TD > bilat

Ipsi > bilat

+19, −95, +16

<0.001

0.002

6426

3

Parietal operculum, supramarginal gyrus (dominant side)

Bilat > contra

Bilat > ipsi

Bilat > TD

+55, −29, +25

<0.001

0.002

3483

  1. TD, typically developing; uCP, unilateral Cerebral Palsy; CST, corticospinal tract; M1, primary motor cortex; p-unc, p-uncorrected; FDR, False Discovery Rate.