Figure 2 | Scientific Reports

Figure 2

From: Glutamate induces synthesis of thrombogenic peptides and extracellular vesicle release from human platelets

Figure 2

Glutamate induces generation of EVs from platelets. (A) Dose-dependent rise in EVs released from glutamate-stimulated platelets. (B) Release of EVs from platelets pre-treated with glutamate, CNQX, EGTA, nocodazole or A23187 as indicated. (C,D) Binding of fluorescent fibrinogen to platelets pre-treated with non-fluorescent fibrinogen, EDTA and vehicle as indicated. Bar diagrams represent atleast 5 independent experiments (mean ± SEM). *P < 0.03 as compared to resting platelets; #P < 0.03 as compared to glutamate-stimulated platelets.

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