Figure 1

MDM morphology and frequency. (a and b) Representative image (AxioVert 200 M, Zeiss, 200× original magnification) of MDMs obtained from healthy subjects and CAD patients (top); frequency in round, spindle, and undefined MDMs in healthy subjects and in CAD patients (bottom). Inset, frequency in round, spindle, and undefined MDMs in stable angina (SA) and acute myocardial infarction (AMI) patients. Data are expressed as the mean ± SD, and they derive from independent cultures obtained from 25 healthy subjects and 50 CAD patients (19 SA and 31 AMI patients). *P < 0.001 round versus spindle and versus undefined MDMs, **P < 0.0001 round versus spindle and versus undefined MDMs.