Table 2 Univariate and multivariate analysis for risk factors of mortality in AL cardiac amyloidosis with heart failure.

From: Predictors of Mortality in Light Chain Cardiac Amyloidosis with Heart Failure

 

Univariate Hazard Ratio

P-Value

Multivariate Hazard Ratio

P-Value

RWT

4.40 (1.87–10.30)

<0.0001

6.70 (2.45–18.30)

<0.001

NYHA Class

2.91 (2.14–3.97)

<0.001

1.50 (1.02–2.2)

0.04

Log BNP

1.93 (1.58–2.38)

<0.001

1.45 (1.15–1.81)

<0.01

Age (years)

1.04 (1.02–1.06

<0.0001

1.04 (1.01–1.06)

<0.01

CRP

1.02 (1.00–1.03)

<0.01

1.02 (1.00–1.04)

0.01

Female Sex

0.87 (0.60–1.26)

0.47

Atrial Fibrillation

1.70 (1.14–2.52)

<0.01

Systolic Blood Pressure

0.99 (0.98–1.00)

0.11

Troponin I

1.14 (0.95–1.35)

0.16

MDRD eGFR (mL/min/1.73 m2)

0.99 (0.98–1.00)

0.051

LVEF (%)

0.97 (0.95–0.99)

<0.0001

IVS (mm)

1.14 (1.05–1.23)

<0.001

LV mass index (g/m2)

0.99 (0.99–1.00)

0.88

dFLC

1.0004 (1.0001–1.0007)

0.0008

QRS duration (ms) on EKG

1.003 (0.99–1.01)

0.44

  1. NYHA, New York Heart Association; BNP, brain natriuretic peptide; CRP, C-reactive protein; MDRD eGFR, glomerular filtration rate by Modification of Diet in Renal Disease equation; LVEF; left ventricular ejection fraction; RWT, relative wall thickness; IVS, interventricular septum; dFLC, difference between involved and uninvolved light chains; EKG, electrocardiogram.