Figure 3 | Scientific Reports

Figure 3

From: Computational analysis of single-cell transcriptomics data elucidates the stabilization of Oct4 expression in the E3.25 mouse preimplantation embryo

Figure 3

Expression of Oct4 and several chromatin remodellers is stabilized at high level in E3.25-HNCs. (A) Heat map of the expression of the 80 top-ranked E3.25 HNC-h-DEGs in decreasing order of significance. The colour bar codifies the gene expression in log2 scale. Higher gene expression corresponds to redder colour. The table to the right annotates GO terms: C (Chromatin remodellers), T (Transcription factor activity), H (Hypoxia), J (Cell junction), P (Plasma membrane), M (Mitochondrion), E (Endoplasmic reticulum), G (Golgi apparatus). (B). Histograms showing the ability of the top-ranked HNC-h-DEGs (Bsg, Ctnnb1, Fgfr1 and Oct4) to discriminate between the E3.25-LNC (blue bars) and E3.25-HNC (red bars) populations.

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