Figure 3
High field DTI-MRI and histopathology correlation results for rectal cancer tissue specimen 2. (a) An MRI TurboRARE image was used as the reference image to obtain the same slice on the DTI-MRI dataset as histopathology for analysis. The DTI-MRI images shown are (b) A0, (c) ADC map, and (d) direction encoded colour fractional anisotropy map. (e) Histopathology haematoxylin and eosin (H&E) stain with a region of cancer zoomed in. (f) Histopathology masson trichome stain with a region of mature fibrous tissue zoomed in. The direction encoded colour fractional anisotropy map was the best DTI-MRI derived image to identify fibrous tissue within the cancer specimen; fibrous tissue had brighter signal intensity and higher fractional anisotropy value than cancer.
